CALL FOR PAPERS Cellular Mechanisms of Tissue Fibrosis PKC /midkine pathway drives hypoxia-induced proliferation and differentiation of human lung epithelial cells
نویسندگان
چکیده
Hanying Zhang, Miyako Okamoto, Evgeniy Panzhinskiy, W. Michael Zawada, and Mita Das Department of Animal Sciences, University of Wyoming, Laramie, Wyoming; Kawahara Clinic, Tokyo, Japan; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, British Columbia, Canada; Department of Geriatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas; and Department of Internal Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas
منابع مشابه
PKCδ/midkine pathway drives hypoxia-induced proliferation and differentiation of human lung epithelial cells.
Epithelial cells are key players in the pathobiology of numerous hypoxia-induced lung diseases. The mechanisms mediating such hypoxic responses of epithelial cells are not well characterized. Earlier studies reported that hypoxia stimulates protein kinase C (PKC)δ activation in renal cancer cells and an increase in expression of a heparin-binding growth factor, midkine (MK), in lung alveolar ep...
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